Letrozole (Femara) is an effective inhibitor of aromatase, an enzyme that is responsible for the synthesis of estrogen in the body. The drug blocks the action of the enzyme, thereby preventing the conversion of testosterone to estrogens.

This drug is approved by the FDA for use in the treatment of breast cancer on its early stages in women.

Thanks to the ability to suppress estrogenic activity, this drug is widely used in sports. Its main users are athletes who apply aromatized Androgenic Anabolic Steroids (AAS).

The drug is different from other similar, it is extremely powerful, and leaves its competitors far behind. The principle of action is significantly different from competitors, it does not act on the estrogens themselves, it prevents their production in the organism. The effect of this drug is so effective that the decreasing of estrogen in the blood occurs to a level of 15%.

The drug is present on the market since 1999 and available in tablets for oral using in a dosage of 25 mg.


For regular AAS users there are 2 ways of applying:

  1. Adding the drug to the AAS course.

  2. Using during the post-course therapy.

Applying on the course. The dosage is 12.5 mg (a half of the tablet) after the meal in a day.

Applying during the PCTThe drug is also used every other day but at a higher dosage, 25 mg for 10 days, after that the dosage is reduced twice and the drug is taken for another two weeks. After the course of Letrozole, you should make a pause.

The total time of application should not exceed 4 weeks.


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