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3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, is a psychoactive drug used primarily as a recreational drug. Desired effects include increased empathy, euphoria, and heightened sensations.
Biological half-life: (R)-MDMA: 5.8 ± 2.2 hours; (S)-MDMA: 3.6 ± 0.9 hours
Onset of action: 30-45 minutes (by mouth)
Duration of action: 4-6 hours
Metabolism: Liver, CYP450 extensively involved, including CYP2D6
Metabolites: MDA, HMMA, HMA, DHA, MDP2P, MDOH
Addiction liability: Low-moderate.
How do people use MDMA?
People who use MDMA usually take it as a capsule or tablet, though some swallow it in liquid form orsnort the powder. The popular nickname Molly (slang for “molecular”) often refers to the supposedly “pure” crystalline powder form of MDMA, usually sold in capsules. However, people who purchase powder or capsules sold as Molly often actually get other drugs such as synthetic cathinones (“bath
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